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Efficacy of Linaclotide in Functional Dyspepsia and Constipation‐Predominant Irritable Bowel Syndrome Overlap: A Randomized Trial

Linaclotide is effective in relieving constipation‐predominant irritable bowel syndrome symptoms. However, few studies focus on the efficacy of linaclotide for overlapping symptoms of functional dyspepsia among irritable bowel syndrome patients.… Click to show full abstract

Linaclotide is effective in relieving constipation‐predominant irritable bowel syndrome symptoms. However, few studies focus on the efficacy of linaclotide for overlapping symptoms of functional dyspepsia among irritable bowel syndrome patients. This study aimed to assess the efficacy of linaclotide compared with lactulose in patients with functional dyspepsia and constipation‐predominant irritable bowel syndrome overlap.

Keywords: efficacy linaclotide; predominant irritable; bowel syndrome; constipation predominant; irritable bowel

Journal Title: Journal of Gastroenterology and Hepatology
Year Published: 2025

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