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Effect of Metabolic Syndrome on Late‐Life Depression: Associations with Disease Severity and Treatment Resistance

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Metabolic syndrome (MetS) is the co‐occurrence of obesity and metabolic derangements. Prior research implicates MetS in prolongation of the course of depression in older adults, but its effect on antidepressant… Click to show full abstract

Metabolic syndrome (MetS) is the co‐occurrence of obesity and metabolic derangements. Prior research implicates MetS in prolongation of the course of depression in older adults, but its effect on antidepressant response is unknown in this population. The objective was to determine whether MetS and related metabolic dyscrasias are associated with decreased rate of remission from depression in older adults treated pharmacologically for depression.

Keywords: depression; syndrome late; effect metabolic; late life; metabolic syndrome

Journal Title: Journal of the American Geriatrics Society
Year Published: 2017

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