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Association between cognitive impairment and oral anticancer agent use in older patients with metastatic renal cell carcinoma

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Kidney cancer is the fastest‐growing cancer diagnosis in the developed world. About 16% of new cases are stage IV, which has a low five‐year survival rate. Many patients with metastatic… Click to show full abstract

Kidney cancer is the fastest‐growing cancer diagnosis in the developed world. About 16% of new cases are stage IV, which has a low five‐year survival rate. Many patients with metastatic renal cell carcinoma (mRCC) are older and may have mild cognitive impairment or dementia (MCI/D). Given prior reports of patients with dementia initiating less cancer therapy and the importance of oral anticancer agents (OAAs) in mRCC treatment, we investigated the prevalence of preexisting MCI/D in patients with mRCC and their OAA use.

Keywords: cell carcinoma; renal cell; metastatic renal; cognitive impairment; patients metastatic; oral anticancer

Journal Title: Journal of the American Geriatrics Society
Year Published: 2022

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