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Overnight pulse rate variability and risk of major neurocognitive disorder in older patients with obstructive sleep apnea

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Increasing evidence links obstructive sleep apnea (OSA) to cognitive decline. Autonomic dysfunction assessed by heart rate variability is a promising early biomarker of cognitive impairment in populations without major neurocognitive… Click to show full abstract

Increasing evidence links obstructive sleep apnea (OSA) to cognitive decline. Autonomic dysfunction assessed by heart rate variability is a promising early biomarker of cognitive impairment in populations without major neurocognitive disorder (MND). We aimed to determine whether nocturnal pulse rate variability (PRV) extracted from oximetry signal and OSA severity could predict MND onset among older OSA patients.

Keywords: sleep apnea; rate; rate variability; major neurocognitive; obstructive sleep

Journal Title: Journal of the American Geriatrics Society
Year Published: 2022

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