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Neurophysiologic predictors of individual risk for post‐operative delirium after elective surgery

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Post‐surgical delirium is associated with increased morbidity, lasting cognitive decline, and loss of functional independence. Within a conceptual framework that delirium is triggered by stressors when vulnerabilities exist in cerebral… Click to show full abstract

Post‐surgical delirium is associated with increased morbidity, lasting cognitive decline, and loss of functional independence. Within a conceptual framework that delirium is triggered by stressors when vulnerabilities exist in cerebral connectivity and plasticity, we previously suggested that neurophysiologic measures might identify individuals at risk for post‐surgical delirium. Here we demonstrate the feasibility of the approach and provide preliminary experimental evidence of the predictive value of such neurophysiologic measures for the risk of delirium in older persons undergoing elective surgery.

Keywords: risk post; neurophysiologic predictors; elective surgery; delirium; post

Journal Title: Journal of the American Geriatrics Society
Year Published: 2022

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