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Benefits and harms of oral anticoagulants for atrial fibrillation in nursing home residents with advanced dementia

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Approximately 20% of older persons with dementia have atrial fibrillation (AF). Nearly all have stroke risks that exceed the guideline‐recommended threshold for anticoagulation. Although individuals with dementia develop profound impairments… Click to show full abstract

Approximately 20% of older persons with dementia have atrial fibrillation (AF). Nearly all have stroke risks that exceed the guideline‐recommended threshold for anticoagulation. Although individuals with dementia develop profound impairments and die from the disease, little evidence exists to guide anticoagulant discontinuation, and almost one‐third of nursing home residents with advanced dementia and AF remain anticoagulated in the last 6 months of life. We aimed to quantify the benefits and harms of anticoagulation in this population.

Keywords: nursing home; residents advanced; home residents; benefits harms; atrial fibrillation; advanced dementia

Journal Title: Journal of the American Geriatrics Society
Year Published: 2022

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