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Diffuse Large B‐Cell Lymphoma in a Cynomolgus Monkey

A captive 17‐year‐old male cynomolgus monkey (Macaca fascicularis) developed diffuse large B‐cell lymphoma (DLBCL). This was the first report of DLBCL presenting with a mandible mass and violation of the… Click to show full abstract

A captive 17‐year‐old male cynomolgus monkey (Macaca fascicularis) developed diffuse large B‐cell lymphoma (DLBCL). This was the first report of DLBCL presenting with a mandible mass and violation of the paranasal sinus in a cynomolgus monkey. The neoplasm showed marked microscopical malignant aspects. Immunohistochemical staining showed strong positive expression of CD20. These features may contribute to the diagnosis and therapeutics of DLBCL in NHPs.

Keywords: cell lymphoma; diffuse large; large cell; cynomolgus monkey; cynomolgus

Journal Title: Journal of Medical Primatology
Year Published: 2024

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