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A growing body of evidence from research in rodents and humans has identified insulin as an important neuoregulatory peptide in the brain, where it coordinates diverse aspects of energy balance… Click to show full abstract
A growing body of evidence from research in rodents and humans has identified insulin as an important neuoregulatory peptide in the brain, where it coordinates diverse aspects of energy balance and peripheral glucose homeostasis. This review discusses where and how insulin interacts within the brain and evaluates the physiological and pathophysiological consequences of central insulin signalling in metabolism, obesity and type 2 diabetes.
Keywords:
insulin;
glucose homeostasis;
energy;
insulin action;
brain
Journal Title: Journal of Neuroendocrinology
Year Published: 2017
Link to full text (if available)
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Journal Title: Journal of Neuroendocrinology
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!