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High rate of Ki‐67 increase in entero‐pancreatic NET relapses after surgery with curative intent

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Neuroendocrine neoplasms (NENs) present with advanced disease at diagnosis in up to 28% of cases, precluding the possibility of curative‐intent surgery. Histopathological heterogeneity of this disease can be observed inter‐individually… Click to show full abstract

Neuroendocrine neoplasms (NENs) present with advanced disease at diagnosis in up to 28% of cases, precluding the possibility of curative‐intent surgery. Histopathological heterogeneity of this disease can be observed inter‐individually as well as intra‐individually during disease course. The present study aimed to assess the frequency of Ki‐67 change after radical surgery, in a series of patients with radically resected entero‐pancreatic neuroendocrine tumors (EP‐NETs).

Keywords: increase entero; entero pancreatic; rate increase; high rate; curative intent

Journal Title: Journal of Neuroendocrinology
Year Published: 2022

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