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Comparison of the therapeutic efficacy and safety of combined oral tranexamic acid and topical hydroquinone 4% treatment vs. topical hydroquinone 4% alone in melasma: a parallel‐group, assessor‐ and analyst‐blinded, randomized controlled trial with a short‐term follow‐up

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Melasma's high prevalence and profound psychological impact on patients necessitate efficacious, economical, and safe therapeutic interventions. Adjunctive therapies such as tranexamic acid (TA) can enhance the therapeutic effect of standard… Click to show full abstract

Melasma's high prevalence and profound psychological impact on patients necessitate efficacious, economical, and safe therapeutic interventions. Adjunctive therapies such as tranexamic acid (TA) can enhance the therapeutic effect of standard treatments like hydroquinone 4% cream (HQ).

Keywords: hydroquinone; efficacy safety; tranexamic acid; comparison therapeutic; therapeutic efficacy; topical hydroquinone

Journal Title: Journal of Cosmetic Dermatology
Year Published: 2017

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