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Elastin microfibril interface‐located protein 1 and its catabolic enzyme, cathepsin K, regulate the age‐related structure of elastic fibers in the skin

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The elastic fiber structure becomes shorter, thicker, and curved with age. Nonetheless, the proteins and catabolic enzymes influencing the maintenance of and change in the three‐dimensional (3D) structure of elastic… Click to show full abstract

The elastic fiber structure becomes shorter, thicker, and curved with age. Nonetheless, the proteins and catabolic enzymes influencing the maintenance of and change in the three‐dimensional (3D) structure of elastic fibers remain unknown. This study aimed to identify the proteins involved in the maintenance and degeneration of elastic fiber structures.

Keywords: structure; structure elastic; microfibril interface; elastin microfibril; age; elastic fibers

Journal Title: Journal of Cosmetic Dermatology
Year Published: 2022

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