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Sensitive ex vivo human skin transdermal assay testing method with mass spectrometric analysis for cosmetics application

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Cosmetics manufacturers are focused on cosmetic delivery systems into the skin, but the level of diffusion of the systems in the skin tissues is not well understood. The current methods,… Click to show full abstract

Cosmetics manufacturers are focused on cosmetic delivery systems into the skin, but the level of diffusion of the systems in the skin tissues is not well understood. The current methods, such as Franz diffusion, assess analyte diffusion in the whole skin or artificial membranes, which has limitations for understanding skin delivery systems.

Keywords: skin transdermal; skin; transdermal assay; sensitive vivo; human skin; vivo human

Journal Title: Journal of Cosmetic Dermatology
Year Published: 2022

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