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An improved explants culture method: Sustainable isolation of keloid fibroblasts with primary characteristics

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Keloid (KD) is a complex fibroproliferative disease, but the exact mechanisms underlying keloid pathogenesis remain to be elucidated. The primary keloid fibroblasts (KFs) culture in vitro has always been a… Click to show full abstract

Keloid (KD) is a complex fibroproliferative disease, but the exact mechanisms underlying keloid pathogenesis remain to be elucidated. The primary keloid fibroblasts (KFs) culture in vitro has always been a fundamental measure to study the pathogenesis of keloid. However, the traditional primary culture methods have some limitations, such as a long culture cycle, low specimen utilization rate and so on.

Keywords: culture; culture method; explants culture; improved explants; keloid fibroblasts

Journal Title: Journal of Cosmetic Dermatology
Year Published: 2022

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