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Platinum‐based chemotherapy is widely used for epithelial ovarian cancer (EOC). As high as 20–25% of EOC patients will not respond to the initial chemotherapy. Accumulated evidences have implied that DNA… Click to show full abstract
Platinum‐based chemotherapy is widely used for epithelial ovarian cancer (EOC). As high as 20–25% of EOC patients will not respond to the initial chemotherapy. Accumulated evidences have implied that DNA methylation may serve as a potential bio‐marker for chemotherapy‐resistant phenotypic screening; however, the pattern underlying primary platinum resistance remains unclear.
Keywords:
platinum resistance;
dna methylome;
epithelial ovarian;
ovarian cancer
Journal Title: Journal of Obstetrics and Gynaecology Research
Year Published: 2021
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Journal Title: Journal of Obstetrics and Gynaecology Research
Year Published: 2021
Link to full text (if available)
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recommendations!