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Prenatal diagnosis of mucopolysaccharidoses type II by two‐dimensional electrophoresis and mass spectrometry in amniotic fluid

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To introduce a quantitative determination of heparan sulfate and dermatan sulfate by mass spectrometry and to compare it with two‐dimensional electrophoresis of the glycosaminoglycans in the amniotic fluid for the… Click to show full abstract

To introduce a quantitative determination of heparan sulfate and dermatan sulfate by mass spectrometry and to compare it with two‐dimensional electrophoresis of the glycosaminoglycans in the amniotic fluid for the prenatal diagnosis of mucopolysaccharidoses type II (MPS II).

Keywords: two dimensional; mass spectrometry; amniotic fluid; diagnosis mucopolysaccharidoses; prenatal diagnosis; dimensional electrophoresis

Journal Title: Journal of Obstetrics and Gynaecology Research
Year Published: 2022

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