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CTLA‐4 polymorphism contributes to the genetic susceptibility of epithelial ovarian cancer

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Cytotoxic T‐lymphocyte antigen‐4 (CTLA‐4), an inhibitory molecule on T‐cells, plays a key role in tumorigenesis and progression. In the present study, we investigated the effects of three polymorphisms in the… Click to show full abstract

Cytotoxic T‐lymphocyte antigen‐4 (CTLA‐4), an inhibitory molecule on T‐cells, plays a key role in tumorigenesis and progression. In the present study, we investigated the effects of three polymorphisms in the CTLA‐4 gene on the risk of epithelial ovarian cancer and the clinical outcomes of patients.

Keywords: polymorphism contributes; ctla polymorphism; ovarian cancer; epithelial ovarian

Journal Title: Journal of Obstetrics and Gynaecology Research
Year Published: 2022

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