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Preliminary mechanism in fetal alloimmune thrombocytopenia associated with anti‐HPA 15b antibodies

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Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a bleeding disease that can cause fetal hydrops, a rare but life‐threatening condition in which abnormal amounts of fluid accumulate in one or… Click to show full abstract

Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a bleeding disease that can cause fetal hydrops, a rare but life‐threatening condition in which abnormal amounts of fluid accumulate in one or two areas of the fetus's body. A case of FNAIT with fetal hydrops caused by anti‐HPA‐15b antibodies was involved in this study, as we investigated whether or not anti‐HPA‐15b antibodies can induce endothelial angiogenesis and apoptosis.

Keywords: hpa 15b; alloimmune thrombocytopenia; 15b antibodies; anti hpa

Journal Title: Journal of Obstetrics and Gynaecology Research
Year Published: 2022

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