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Functional Neurosonology Reveals Impaired Cerebrovascular Reactivity in Multiple Sclerosis

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Vascular aspects like global cerebral hypoperfusion are frequently reported in patients with multiple sclerosis (MS). Although mechanistic question remains unanswered, this hemodynamic impairment may be caused by a widespread endothelial… Click to show full abstract

Vascular aspects like global cerebral hypoperfusion are frequently reported in patients with multiple sclerosis (MS). Although mechanistic question remains unanswered, this hemodynamic impairment may be caused by a widespread endothelial dysfunction. Furthermore, impaired cerebrovascular reactivity (CVR) has been described in patients with MS by means of hypercapnic perfusion magnetic resonance imaging (MRI). We sought to further evaluate potential hemodynamic restriction in patients with MS using functional sonographic methods.

Keywords: multiple sclerosis; cerebrovascular reactivity; impaired cerebrovascular; functional neurosonology

Journal Title: Journal of Neuroimaging
Year Published: 2019

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