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Pediatric Posterior Fossa Medulloblastoma: The Role of Diffusion Imaging in Identifying Molecular Groups

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The molecular groups WNT activated (WNT), Sonic hedgehog activated (SHH), group 3, and group 4 are biologically and clinically distinct forms of medulloblastoma. We evaluated apparent diffusion coefficient (ADC) values’… Click to show full abstract

The molecular groups WNT activated (WNT), Sonic hedgehog activated (SHH), group 3, and group 4 are biologically and clinically distinct forms of medulloblastoma. We evaluated apparent diffusion coefficient (ADC) values’ utility in differentiating/predicting medulloblastoma groups at the initial diagnostic imaging evaluation and prior to surgery.

Keywords: fossa medulloblastoma; diffusion; posterior fossa; pediatric posterior; molecular groups

Journal Title: Journal of Neuroimaging
Year Published: 2020

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