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Cortico‐striatal functional connectivity and cerebral small vessel disease: Contribution to mild Parkinsonian signs

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Mild Parkinsonian signs (MPS) are common in older adults. We hypothesized that MPS are associated with lower functional connectivity (FC) in dopamine‐dependent cortico‐striatal networks, and these associations vary with white… Click to show full abstract

Mild Parkinsonian signs (MPS) are common in older adults. We hypothesized that MPS are associated with lower functional connectivity (FC) in dopamine‐dependent cortico‐striatal networks, and these associations vary with white matter hyperintensity (WMH), a risk factor for MPS.

Keywords: mild parkinsonian; cortico striatal; functional connectivity; striatal functional; parkinsonian signs

Journal Title: Journal of Neuroimaging
Year Published: 2021

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