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Classification of multiple sclerosis patients based on structural disconnection: A robust feature selection approach

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Although structural disconnection represents the hallmark of multiple sclerosis (MS) pathophysiology, classification attempts based on structural connectivity have achieved low accuracy levels. Here, we set out to fill this gap,… Click to show full abstract

Although structural disconnection represents the hallmark of multiple sclerosis (MS) pathophysiology, classification attempts based on structural connectivity have achieved low accuracy levels. Here, we set out to fill this gap, exploring the performance of supervised classifiers on features derived from microstructure informed tractography and selected applying a novel robust approach.

Keywords: classification; based structural; multiple sclerosis; structural disconnection

Journal Title: Journal of Neuroimaging
Year Published: 2022

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