The North American Imaging in Multiple Sclerosis (NAIMS) multisite project identified interscanner reproducibility issues with T1‐based whole brain volume (WBV). Lateral ventricular volume (LVV) acquired on T2‐fluid‐attenuated inverse recovery (FLAIR)… Click to show full abstract
The North American Imaging in Multiple Sclerosis (NAIMS) multisite project identified interscanner reproducibility issues with T1‐based whole brain volume (WBV). Lateral ventricular volume (LVV) acquired on T2‐fluid‐attenuated inverse recovery (FLAIR) scans has been proposed as a robust proxy measure. Therefore, we sought to determine the relative magnitude of scanner‐induced T2‐FLAIR‐based LVV and T1‐based WBV measurement errors in relation to clinically meaningful changes.
               
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