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Zonulin and claudin‐5 levels in multisystem inflammatory syndrome and SARS‐CoV‐2 infection in children

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SARS‐CoV‐2 infection in children is generally asymptomatic or mild; however, it can lead to a life‐threatening clinical condition, multisystem inflammatory syndrome in children (MIS‐C), days or weeks after the infection.… Click to show full abstract

SARS‐CoV‐2 infection in children is generally asymptomatic or mild; however, it can lead to a life‐threatening clinical condition, multisystem inflammatory syndrome in children (MIS‐C), days or weeks after the infection. Increased intestinal permeability isa possible triggering factor at the onset of the hyperinflammation associated with MIS‐C. Zonulin and claudin‐5 are involved in intestinal permeability. In this study, we aimed to investigate serum zonulin and claudin‐5 levels in SARS‐CoV‐2 infection and MIS‐C disease.

Keywords: infection; infection children; zonulin claudin; cov infection; sars cov

Journal Title: Journal of Paediatrics and Child Health
Year Published: 2022

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