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A rapidly growing lesion on the lip

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The correct answer is c. Pyogenic granuloma was considered, and the lesion was excised. Histopathological examination confirmed the diagnosis. At 1-month follow-up, there was no recurrence. Pyogenic granuloma (PG) is… Click to show full abstract

The correct answer is c. Pyogenic granuloma was considered, and the lesion was excised. Histopathological examination confirmed the diagnosis. At 1-month follow-up, there was no recurrence. Pyogenic granuloma (PG) is a common vascular proliferation of the skin and mucous membranes. It is not pyogenic or granulomatous, and a reactive vascular response to trauma, female sex hormones, medications, infections or poor oral hygiene (in oral PG) seems to be implicated. PG is more prevalent in children, adolescents and pregnant women. Oral PG is more common in females in the second decade of life. It typically presents as a solitary, pedunculated/sessile erythematous papule, with an erosive or friable surface, with rapid growth over weeks to months, occasionally to a few centimeters. It is usually painless and tends to bleed and ulcerate. In the oral cavity, PG is more common in the gingiva, lips, tongue and buccal mucosa. In a study including 50 cases, 90% involved the gingiva, 6% the lips and 4% the ventral surface of the tongue. It can have cosmetic implications but has no malignant potential. The differential diagnosis of oral PG includes: peripheral giant cell granuloma, peripheral ossifying fibroma, hemangioma, lymphangioma, granulation tissue, traumatic ulcer, Kaposi’s sarcoma, angiosarcoma, non-Hodgkin’s lymphoma, malignancy, syphilis, tuberculous ulcer and cutaneous horn of the lip. PG is a clinical diagnosis and biopsy is necessary if the diagnosis is not clear. Surgical excision is the treatment of choice with the lowest rate of recurrence.

Keywords: diagnosis; growing lesion; lesion lip; rapidly growing; lip; lesion

Journal Title: Journal of Paediatrics and Child Health
Year Published: 2019

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