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Methyl jasmonate: a phytohormone with potential for the treatment of inflammatory bowel diseases

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The phytohormone methyl jasmonate (MeJA) has been identified as a vital cell regulator in plants. This substance is analogous to eicosanoids and similar to that of anti‐inflammatory prostaglandins. In animals… Click to show full abstract

The phytohormone methyl jasmonate (MeJA) has been identified as a vital cell regulator in plants. This substance is analogous to eicosanoids and similar to that of anti‐inflammatory prostaglandins. In animals and in animal cells, it displayed an efficient neuroprotective, anti‐inflammatory and antioxidant action; while in tumoral strains, it demonstrates a potentially highly attractive mechanism of apoptosis induction through various cellular and molecular mechanisms. The aim of the present review was to explore two new hypotheses that explain the action of MeJA, a lipid phytohormone and its potentially anti‐apoptotic mechanism for use as a therapeutic target for future treatment of Inflammatory bowel diseases (IBDs).

Keywords: methyl jasmonate; treatment inflammatory; inflammatory bowel; bowel diseases; inflammatory; phytohormone

Journal Title: Journal of Pharmacy and Pharmacology
Year Published: 2018

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