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Comprehensive drug utilization review in neonates: liposomal amphotericin B

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This drug utilization evaluation aims to review current evidence on safety and efficacy of using liposomal amphotericin B (LAMB) in newborns with candidiasis, and compare it to the conventional preparation.… Click to show full abstract

This drug utilization evaluation aims to review current evidence on safety and efficacy of using liposomal amphotericin B (LAMB) in newborns with candidiasis, and compare it to the conventional preparation. Conventional amphotericin B deoxycholate (DAMB) is more commonly used in newborns, but dose‐limiting adverse effects may compromise its efficacy. This review will examine the advantages and disadvantages of liposomal amphotericin B and define its place in current practice.

Keywords: comprehensive drug; drug utilization; liposomal amphotericin; review

Journal Title: Journal of Pharmacy and Pharmacology
Year Published: 2018

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