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Tumour hypoxia is a major obstacle in cancer therapy that leads to poor prognosis. Therefore, the development of cancer treatments that are effective in hypoxia is necessary. Nitrogen‐containing bisphosphonates (N‐BPs),… Click to show full abstract
Tumour hypoxia is a major obstacle in cancer therapy that leads to poor prognosis. Therefore, the development of cancer treatments that are effective in hypoxia is necessary. Nitrogen‐containing bisphosphonates (N‐BPs), which are used to treat bone disease, are cytotoxic to several cancer cells in normoxia. Therefore, we investigated the cytotoxicity of N‐BPs in cancer cells in hypoxia.
Keywords:
cytotoxic effects;
effects nitrogen;
containing bisphosphonates;
augmentation cytotoxic;
nitrogen containing;
cancer
Journal Title: Journal of Pharmacy and Pharmacology
Year Published: 2018
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Journal Title: Journal of Pharmacy and Pharmacology
Year Published: 2018
Link to full text (if available)
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recommendations!