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Paeonia lactiflora Pall. regulates the NF‐κB‐NLRP3 inflammasome pathway to alleviate cholestasis in rats

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Cholestasis is a critical risk factor for severe hepatic disease or cirrhosis. The anti‐inflammatory effect of Paeonia lactiflora Pall. (PLP), named Chishao in traditional Chinese medicine (TCM), on alpha‐naphthylisothiocyanate (ANIT)‐induced… Click to show full abstract

Cholestasis is a critical risk factor for severe hepatic disease or cirrhosis. The anti‐inflammatory effect of Paeonia lactiflora Pall. (PLP), named Chishao in traditional Chinese medicine (TCM), on alpha‐naphthylisothiocyanate (ANIT)‐induced cholestasis model was tried to be elucidated in this research.

Keywords: lactiflora pall; regulates nlrp3; paeonia lactiflora; pall regulates; nlrp3 inflammasome; cholestasis

Journal Title: Journal of Pharmacy and Pharmacology
Year Published: 2018

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