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It has been proven that extracellular HMGB1 is involved in progression of neurologic disorders, such as stroke, traumatic brain injury, meningitis and epilepsy. Glycyrrhizin (GL) is a direct inhibitor of… Click to show full abstract
It has been proven that extracellular HMGB1 is involved in progression of neurologic disorders, such as stroke, traumatic brain injury, meningitis and epilepsy. Glycyrrhizin (GL) is a direct inhibitor of HMGB1, and blocks HMGB1 release into the extracellular. We aim in this study to investigate the neuroprotective effects of GL in a rat model after lithium‐pilocarpine‐induced status epilepticus (SE).
Keywords:
neuroprotective effects;
pilocarpine induced;
glycyrrhizin;
status epilepticus;
lithium pilocarpine;
induced status
Journal Title: Journal of Pharmacy and Pharmacology
Year Published: 2019
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Journal Title: Journal of Pharmacy and Pharmacology
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!