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Sestrins (SESNs) and sirtuins (SIRTs) are antioxidant and antiapoptotic genes and crucial mediators for lysosomal autophagy regulation that play a pivotal role in the Alzheimer's disease (AD). Recently, statins have… Click to show full abstract
Sestrins (SESNs) and sirtuins (SIRTs) are antioxidant and antiapoptotic genes and crucial mediators for lysosomal autophagy regulation that play a pivotal role in the Alzheimer's disease (AD). Recently, statins have been linked to the reduced prevalence of AD in statin‐prescribed populations yet molecular basis for the neuroprotective action of statins is still under debate.
Keywords:
sirt1 lc3ii;
alteration sesn2;
atorvastatin induced;
induced alteration;
sesn2 sirt1;
effect atorvastatin
Journal Title: Journal of Pharmacy and Pharmacology
Year Published: 2019
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Journal Title: Journal of Pharmacy and Pharmacology
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!