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Regulation of breast cancer resistance protein and P‐glycoprotein by ezrin, radixin and moesin in lung, intestinal and renal cancer cell lines

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Ezrin (Ezr), radixin (Rdx) and moesin (Msn) (ERM) proteins anchor other proteins to the cell membrane, serving to regulate their localization and function. Here, we examined whether ERM proteins functionally… Click to show full abstract

Ezrin (Ezr), radixin (Rdx) and moesin (Msn) (ERM) proteins anchor other proteins to the cell membrane, serving to regulate their localization and function. Here, we examined whether ERM proteins functionally regulate breast cancer resistance protein (BCRP) and P‐glycoprotein in cell lines derived from lung, intestinal and renal cancers.

Keywords: cancer resistance; resistance protein; cell lines; lung intestinal; breast cancer; cancer

Journal Title: Journal of Pharmacy and Pharmacology
Year Published: 2020

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