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Cost‐effectiveness of Interventional therapies for management of Treatment‐resistant hypertension: systematic review of pharmacoeconomic studies

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Treatment resistant hypertension (TRH) is defined as uncontrolled blood pressure (>140/90 mm Hg) after treatment with the intensified dose of three standard antihypertensive drugs. Management of TRH involves addition of… Click to show full abstract

Treatment resistant hypertension (TRH) is defined as uncontrolled blood pressure (>140/90 mm Hg) after treatment with the intensified dose of three standard antihypertensive drugs. Management of TRH involves addition of fourth line drugs on standard care or interventional therapies (Renal denervation, Baroreceptor activation, Central venous anastomosis). However, evidence concerning cost‐effectiveness of interventional therapies is inconclusive. Objective: This systematic review was conducted to extract the level of evidence on cost‐effectiveness of interventional therapies for TRH.

Keywords: effectiveness interventional; treatment resistant; interventional therapies; resistant hypertension; cost effectiveness

Journal Title: Journal of Pharmaceutical Health Services Research
Year Published: 2020

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