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Essentials Required warfarin doses for mechanical heart valves vary greatly. A two‐stage extreme phenotype design was used to identify novel warfarin dose associated mutation. We identified a group of variants… Click to show full abstract
Essentials Required warfarin doses for mechanical heart valves vary greatly. A two‐stage extreme phenotype design was used to identify novel warfarin dose associated mutation. We identified a group of variants significantly associated with extreme warfarin dose. Four novel identified mutations account for 2.2% of warfarin dose discrepancies.
Keywords:
novel;
stage extreme;
extreme phenotype;
two stage
Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2017
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Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!