Photo from wikipedia
Essentials The C‐terminus of tissue factor pathway inhibitor (TFPIα) binds to the B‐domain of factor V (FV). The functional consequences of this interaction were investigated in plasma and model systems.… Click to show full abstract
Essentials The C‐terminus of tissue factor pathway inhibitor (TFPIα) binds to the B‐domain of factor V (FV). The functional consequences of this interaction were investigated in plasma and model systems. The TFPIα C‐terminus inhibited thrombin generation in plasma, but not in the presence of FVa. The TFPIα C‐terminus inhibited FV activation by preventing cleavage at Arg1545.
Keywords:
terminus;
factor pathway;
pathway inhibitor;
tissue factor;
terminus tissue;
factor
Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!