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Hierarchical organization of the hemostatic response to penetrating injuries in the mouse macrovasculature

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Essentials Methods were developed to image the hemostatic response in mouse femoral arteries in real time. Penetrating injuries produced thrombi consisting primarily of platelets. Similar to arterioles, a core‐shell architecture… Click to show full abstract

Essentials Methods were developed to image the hemostatic response in mouse femoral arteries in real time. Penetrating injuries produced thrombi consisting primarily of platelets. Similar to arterioles, a core‐shell architecture of platelet activation occurs in the femoral artery. Differences from arterioles included slower platelet activation and reduced thrombin dependence.

Keywords: hierarchical organization; penetrating injuries; hemostatic response; organization hemostatic; response penetrating

Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2017

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