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Essentials New strategies are needed to inhibit thrombosis and intimal hyperplasia (IH) in vein grafts (VG). We studied effects of apyrase (APT102) on VGs and smooth muscle and endothelial cells… Click to show full abstract
Essentials New strategies are needed to inhibit thrombosis and intimal hyperplasia (IH) in vein grafts (VG). We studied effects of apyrase (APT102) on VGs and smooth muscle and endothelial cells (SMC/EC). APT102 inhibited thrombosis, SMC migration, and IH without impairing hemostasis or EC recovery. Apyrase APT102 is a single‐drug approach to inhibit multiple processes that cause VG failure.
Keywords:
apyrase apt102;
intimal hyperplasia;
thrombosis;
vein grafts;
hyperplasia vein;
thrombosis intimal
Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2017
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Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!