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Predictive performance of the CHA2DS2‐VASc rule in atrial fibrillation: a systematic review and meta‐analysis

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Essentials The widely recommended CHA2DS2‐VASc shows conflicting results in contemporary validation studies. We performed a systematic review and meta‐analysis of 19 studies validating CHA2DS2‐VASc. There was high heterogeneity in stroke… Click to show full abstract

Essentials The widely recommended CHA2DS2‐VASc shows conflicting results in contemporary validation studies. We performed a systematic review and meta‐analysis of 19 studies validating CHA2DS2‐VASc. There was high heterogeneity in stroke risks for different CHA2DS2‐VASc scores. This was not explained by differences between setting of care, or by performing meta‐regression.

Keywords: review meta; systematic review; cha2ds2 vasc; vasc; meta analysis

Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2017

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