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Effect of extended‐duration thromboprophylaxis on venous thromboembolism and major bleeding among acutely ill hospitalized medical patients: a bivariate analysis

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Essentials Anticoagulants prevent venous thromboembolism but may be associated with greater bleeding risks. Bivariate analysis assumes a non‐linear relationship between efficacy and safety outcomes. Extended full‐dose betrixaban is favorable over… Click to show full abstract

Essentials Anticoagulants prevent venous thromboembolism but may be associated with greater bleeding risks. Bivariate analysis assumes a non‐linear relationship between efficacy and safety outcomes. Extended full‐dose betrixaban is favorable over standard enoxaparin in bivariate endpoint. Clinicians must weigh efficacy and safety outcomes in decision‐making on thromboprophylaxis.

Keywords: venous thromboembolism; extended duration; bivariate analysis; effect extended

Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2017

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