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Metabolomic analysis of 92 pulmonary embolism patients from a nested case–control study identifies metabolites associated with adverse clinical outcomes

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Essentials Risk‐stratification often fails to predict clinical deterioration in pulmonary embolism (PE). First‐ever high‐throughput metabolomics analysis of risk‐stratified PE patients. Changes in circulating metabolites reflect a compromised energy metabolism in… Click to show full abstract

Essentials Risk‐stratification often fails to predict clinical deterioration in pulmonary embolism (PE). First‐ever high‐throughput metabolomics analysis of risk‐stratified PE patients. Changes in circulating metabolites reflect a compromised energy metabolism in PE. Metabolites play a key role in the pathophysiology and risk stratification of PE.

Keywords: pulmonary embolism; analysis pulmonary; embolism; embolism patients; metabolomic analysis

Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2018

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