Photo by nci from unsplash
Essentials Bovine (HBI) and porcine (HPI) heparins differ in structure and anticoagulant activity. Protamine‐neutralization was evaluated on a variety of physical‐chemical methods. HBI requires more protamine than HPI to fully… Click to show full abstract
Essentials Bovine (HBI) and porcine (HPI) heparins differ in structure and anticoagulant activity. Protamine‐neutralization was evaluated on a variety of physical‐chemical methods. HBI requires more protamine than HPI to fully neutralize its anticoagulant activity. Protamine preferentially removes higher‐sulfated chains of HBI while HPI is evenly precipitated.
Keywords:
chemical pharmacological;
different animal;
neutralization heparins;
pharmacological aspects;
aspects neutralization;
heparins different
Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!