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Essentials At low pH and low salt concentrations: Maximal conformational change of PF4 upon complexation with heparin occurs. Changing physicochemical conditions may become an approach to better discriminate the signal… Click to show full abstract
Essentials At low pH and low salt concentrations: Maximal conformational change of PF4 upon complexation with heparin occurs. Changing physicochemical conditions may become an approach to better discriminate the signal of platelet‐activating‐ and nonactivating PF4/H Abs in antigen tests.
Keywords:
heparin;
platelet activating;
reactivity platelet;
activating nonplatelet;
pf4
Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2019
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Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!