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The (non‐)sense of detecting anti‐cardiolipin and anti‐β2glycoprotein I IgM antibodies in the antiphospholipid syndrome

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The antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy morbidity with the persistent presence of lupus anticoagulant (LAC), anti‐cardiolipin (aCL) and/or anti‐β2glycoprotein I (aβ2GPI) antibodies of the immunoglobulin G/immunoglobulin… Click to show full abstract

The antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy morbidity with the persistent presence of lupus anticoagulant (LAC), anti‐cardiolipin (aCL) and/or anti‐β2glycoprotein I (aβ2GPI) antibodies of the immunoglobulin G/immunoglobulin M (IgG/IgM) isotype. However, the role of aCL and aβ2GPI IgM as a serologic marker in APS is debated.

Keywords: anti cardiolipin; antiphospholipid syndrome; anti 2glycoprotein; sense detecting; non sense

Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2019

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