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Sepsis triggers dysfunction of coagulation and fibrinolytic systems leading to disseminated intravascular coagulation (DIC) that contributes to organ failure and death. Fondaparinux (FPX) is a synthetic pentasaccharide that binds to… Click to show full abstract
Sepsis triggers dysfunction of coagulation and fibrinolytic systems leading to disseminated intravascular coagulation (DIC) that contributes to organ failure and death. Fondaparinux (FPX) is a synthetic pentasaccharide that binds to antithrombin (AT) and selectively inhibits factor (F) Xa and other upstream coagulation proteases but not thrombin (T).
Keywords:
sepsis;
fondaparinux;
pentasaccharide reduces;
fondaparinux pentasaccharide;
reduces sepsis
Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2019
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Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!