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Pharmacokinetics, immunogenicity, safety, and preliminary efficacy of subcutaneous turoctocog alfa pegol in previously treated patients with severe hemophilia A (alleviate 1)

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The current standard of care for patients with hemophilia A is regular prophylaxis with factor VIII (FVIII) administered intravenously. Interest in subcutaneous (s.c.) administration, to potentially increase convenience, reduce the… Click to show full abstract

The current standard of care for patients with hemophilia A is regular prophylaxis with factor VIII (FVIII) administered intravenously. Interest in subcutaneous (s.c.) administration, to potentially increase convenience, reduce the treatment burden and improve compliance, is increasing.

Keywords: subcutaneous turoctocog; preliminary efficacy; efficacy subcutaneous; immunogenicity safety; safety preliminary; pharmacokinetics immunogenicity

Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2019

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