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Regulated protein synthesis is essential for megakaryocyte (MK) and platelet functions, including platelet production and activation. PDK1 (phosphoinositide‐dependent kinase 1) regulates platelet functional responses and has been associated with circulating… Click to show full abstract
Regulated protein synthesis is essential for megakaryocyte (MK) and platelet functions, including platelet production and activation. PDK1 (phosphoinositide‐dependent kinase 1) regulates platelet functional responses and has been associated with circulating platelet counts. Whether PDK1 also directly regulates protein synthetic responses in MKs and platelets, and platelet production by MKs, remains unknown.
Keywords:
phospho inositide;
dependent kinase;
inositide dependent;
regulates signal;
kinase regulates
Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2020
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Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!