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Factor XII (FXII) is a plasma serine protease that initiates the intrinsic pathway of blood coagulation upon contact with anionic substances, such as the sulfated glycolipid sulfatide. Annexins (ANXs) have… Click to show full abstract
Factor XII (FXII) is a plasma serine protease that initiates the intrinsic pathway of blood coagulation upon contact with anionic substances, such as the sulfated glycolipid sulfatide. Annexins (ANXs) have been implicated in the regulation of the blood coagulation reaction by binding to anionic surfaces composed of phospholipids and sulfated glycoconjugates, but their physiological importance is only partially understood.
Keywords:
coagulation;
factor xii;
annexin inhibits;
inhibits sulfatide
Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2020
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Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!