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Essentials Tranexamic acid (TXA) is an antifibrinolytic drug used to reduce bleeding. Assaying plasmin generation (PG) in plasma detects clinically relevant TXA levels in vitro and ex vivo. 3.1‐16.2 µg/mL… Click to show full abstract
Essentials Tranexamic acid (TXA) is an antifibrinolytic drug used to reduce bleeding. Assaying plasmin generation (PG) in plasma detects clinically relevant TXA levels in vitro and ex vivo. 3.1‐16.2 µg/mL TXA half‐maximally inhibits PG in plasma from women undergoing cesarean delivery. PG velocity shows the strongest dose‐relationship at low TXA concentrations (≤10 µg/mL).
Keywords:
women undergoing;
tranexamic acid;
plasmin generation;
cesarean delivery;
undergoing cesarean
Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2020
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Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!