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Tissue factor pathway inhibitor (TFPI) is an anticoagulant protein required for murine embryonic development. Intrauterine lethality of Tfpi−/− mice occurs at mid‐ and late gestation, the latter of which is… Click to show full abstract
Tissue factor pathway inhibitor (TFPI) is an anticoagulant protein required for murine embryonic development. Intrauterine lethality of Tfpi−/− mice occurs at mid‐ and late gestation, the latter of which is associated with severe cerebrovascular defects. Megakaryocytes produce only the TFPIα isoform, which is stored within platelets and released upon activation.
Keywords:
intrauterine lethality;
mid late;
lethality tfpi;
late gestation;
tfpi
Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2021
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Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!