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GATA1 is an essential transcription factor for both polyploidization and megakaryocyte (MK) differentiation. The polyploidization defect observed in GATA1 variant carriers is not well understood. Click to show full abstract
GATA1 is an essential transcription factor for both polyploidization and megakaryocyte (MK) differentiation. The polyploidization defect observed in GATA1 variant carriers is not well understood.
Keywords:
disrupt myh10;
myh10 silencing;
gata1 pathogenic;
pathogenic variants;
variants disrupt;
silencing megakaryopoiesis
Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2021
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Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!