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First evaluation of the safety, pharmacokinetics, and pharmacodynamics of BAY 2433334, a small molecule targeting coagulation factor XIa

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Coagulation factor XI (FXI) contributes to the development of thrombosis but appears to play a minor role in hemostasis and is, therefore, an attractive anticoagulant drug target. Click to show full abstract

Coagulation factor XI (FXI) contributes to the development of thrombosis but appears to play a minor role in hemostasis and is, therefore, an attractive anticoagulant drug target.

Keywords: coagulation; first evaluation; coagulation factor; safety pharmacokinetics; evaluation safety

Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2021

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